Ep, USP Enrofloxacin CAS 93106-60-6

• Varieties: Infectious Disease Prevention Medicine
• Component: Chemical Synthetic Drugs
• Type: The First Class
• Pharmacodynamic Influential Factors: Repeated Medication
• Storage Method: Moisture Proof
• Veterinary Reg. No.: No
• Model NO.: Enrofloxacin
• Appearance: Light Yellow Crystalline Powder
• Stock: Yes
• Transport Package: Drum
• Specification: EP, USP
• Trademark: SAMREAL
• Origin: China
• HS Code: 29339900
• Production Capacity: 100 Tons Per Year

Product Description

Enrofloxacin [93106-60-6]

Identification
Name		Enrofloxacin
Synonyms		1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Molecular Structure
Molecular Formula		C19H22FN3O3
Molecular Weight		359.40
CAS Registry Number		93106-60-6

 

Test Items	Standard
Appearance	Pale yellowish or light yellow crystalline powder
Solubility	Practically insoluble in water,freely soluble in methylene chloride,slightly soluble in methanol.
Identification	IR:Conforms to the spectrum of enrofloxacin CRS
Appearance of solution	Not more opalescent than reference suspension II and not more intensely coloured reference solution GY4.
Impurity A	≤0.2%
Ralated substance Impurity B Impurity C Unspecified impurity Total impurity	≤0.5% ≤0.2% ≤0.2% ≤1.0%
Ralated substances Ethanol Isoamyl alcohol Methanol Toluene N,N-dimethylformaminde	≤200ppm ≤100ppm ≤200ppm ≤100ppm ≤880ppm
Loss on drying	≤1.0%
Sulphated ash	≤0.1%
Heavy metals	≤ 20 ppm
Assay(on drying basis)	98.5%~101.5%

 

Overdosage/acute toxicity

It is unlikely that an acute overdose of either compound would result in symptoms more serious than either anorexia or vomiting, but the adverse effects noted above could occur. Dogs receiving 10 times the labeled dosage rate of enrofloxacin for at least 14 days developed only vomiting and anorexia. Death did occur in some dogs when fed 25 times the labeled rate for 11 days, however.

• Oral LD₅₀: greater than 5000 mg/kg
• Dermal LD₅₀: greater than 2000 mg/kg
• Inhalation LD₅₀: greater than 3547 mg/m3 (4-hour exposure)
• Eye effects: irritant; reversible in less than 7 days. In cats, it can produce sudden onset blindness when administered by injection, as it is retinotoxic